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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWOX
All Species:
14.55
Human Site:
T49
Identified Species:
24.62
UniProt:
Q9NZC7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZC7
NP_057457.1
414
46677
T49
T
Q
W
E
H
P
K
T
G
K
R
K
R
V
A
Chimpanzee
Pan troglodytes
XP_001144696
363
41022
N13
Y
A
G
L
D
D
T
N
S
E
D
E
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001105944
398
45056
K48
K
T
Q
W
E
H
P
K
T
G
K
R
K
R
V
Dog
Lupus familis
XP_852623
383
43043
Y33
T
T
K
D
G
W
V
Y
Y
A
N
H
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WL8
414
46494
T49
T
Q
W
E
H
P
K
T
G
K
R
K
R
V
A
Rat
Rattus norvegicus
NP_001099658
356
40173
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505354
146
16628
Chicken
Gallus gallus
Q5F389
414
46711
S49
T
Q
W
E
H
P
K
S
G
K
R
K
R
V
A
Frog
Xenopus laevis
NP_001088080
143
16305
Zebra Danio
Brachydanio rerio
Q803A8
412
46303
T49
T
Q
W
E
H
P
K
T
G
K
K
K
R
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLU5
409
46492
R49
P
R
T
G
R
S
K
R
I
T
G
E
L
P
L
Honey Bee
Apis mellifera
XP_395282
414
46992
K49
H
P
R
T
G
R
T
K
T
V
E
G
E
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789399
410
45991
R50
S
H
P
R
T
G
K
R
K
R
I
T
G
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42536
405
43844
S49
Q
S
K
A
D
F
V
S
S
S
L
R
C
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
84.7
82.8
N.A.
93.7
81.1
N.A.
26
83
29.2
71.9
N.A.
48.3
51.2
N.A.
56.2
Protein Similarity:
100
86.2
88.4
87.4
N.A.
96.1
83.8
N.A.
29.4
93
33.3
84.3
N.A.
65.2
66.6
N.A.
73.4
P-Site Identity:
100
0
0
6.6
N.A.
100
0
N.A.
0
93.3
0
86.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
13.3
20
13.3
N.A.
100
0
N.A.
0
100
0
93.3
N.A.
20
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
8
0
0
8
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
0
0
8
15
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
29
8
0
0
0
0
8
8
15
8
15
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
15
8
0
0
29
8
8
8
8
0
0
% G
% His:
8
8
0
0
29
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
8
0
15
0
0
0
43
15
8
29
15
29
8
8
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
8
0
15
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
8
8
8
0
0
29
8
0
0
0
0
0
0
15
15
% P
% Gln:
8
29
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
8
8
8
0
15
0
8
22
15
29
8
8
% R
% Ser:
8
8
0
0
0
8
0
15
15
8
0
0
0
0
0
% S
% Thr:
36
15
8
8
8
0
15
22
15
8
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
8
0
0
0
22
8
% V
% Trp:
0
0
29
8
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _